Linking Invasive and Noninvasive Brain Stimulation

Lukas Goede, MD – Clinician Scientist at Charité Universitätsmedizin Berlin

Dr. Lukas Goede is a clinician-scientist at Charité – Universitätsmedizin Berlin. He began his career as a neurology resident in the Movement Disorders and Neuromodulation Unit at Charité in 2020. From 2024 to 2025, he served as a research fellow at the Center for Brain Circuit Therapeutics at Brigham & Women’s Hospital in Boston, working alongside Andreas Horn and Michael Fox on DBS network mapping and multifocal tDCS. His research focuses on identifying brain networks through DBS network mapping and developing noninvasive strategies to modulate them. By combining clinical experience with network-based research, his goal is to improve outcomes for patients with Parkinson’s disease and other movement disorders.

About the Webinar

This webinar will focus on bridging invasive and noninvasive neuromodulation in Parkinson’s disease. We will discuss how DBS network mapping can be used to identify brain networks that may be targeted noninvasively and present results from a recent randomized clinical trial in Parkinson’s disease patients. In addition, we will explore whether transcranial direct current stimulation (tDCS) can enhance levodopa challenge testing, offering a potential predictor of deep brain stimulation outcomes. Together, these findings highlight the role of noninvasive stimulation both as a therapeutic tool and as a means to optimize patient selection for DBS.